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Tesofensine

Original price was: $200.00.Current price is: $160.00.

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Tesofensine is a synthetic tropane derivative that has been studied for its interaction with the central nervous system, particularly in relation to monoamine transporters. Structurally classified as a triple monoamine reuptake inhibitor, it exhibits high-affinity binding to presynaptic transporters of serotonin (5-HT), dopamine (DA), and norepinephrine (NE) in preclinical settings.

Molecular Formula: C₁₇H₂₃Cl₂NO
Form: Tablet (for laboratory handling only)
Concentration: 500mcg per tablet
Quantity: 30 tablets per container
Purity: ≥99% (HPLC-Verified)
Storage: Store in a cool, dry, and dark environment; optimal at 2–8°C.

Research Applications

Tesofensine is frequently used in experimental settings to study neurotransmitter signaling and central monoaminergic system regulation. Key areas of laboratory interest include:

  • Dopaminergic and serotonergic response modeling

  • Appetite regulation and energy balance signalling

  • Neurochemical mapping of transporter interactions

  • Monoamine reuptake blockade kinetics

Due to its ability to inhibit multiple monoamine transporters simultaneously, Tesofensine offers a unique research profile distinct from more selective ligands.

Key Research Notes

  • Selectivity: Exhibits broad-spectrum inhibition of SERT, NET, and DAT.

  • Pharmacological Focus: Often compared to other transporter inhibitors in mechanistic studies on synaptic clearance and neurotransmitter recycling.

  • Lab Use Format: Solid-phase tablet allows for precise handling, weighing, and solubility experiments.

Compliance & Usage

This product is strictly intended for in vitro laboratory research and analytical purposes. It is not for human or veterinary use, and not for consumption. No claims are made regarding its therapeutic use or benefit. This compound is not FDA-approved and should only be handled by qualified personnel in research-controlled environments.

 

View the lab results: https://janoshik.com/tests/34608-Tesofensine_500_mcg_QZTUKW1FPRGJ

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