CJC-1295 No DAC, also referred to as Modified GRF (1-29), is a synthetic analog of growth hormone-releasing hormone (GHRH). It is widely used in research settings focused on pulsatile growth hormone secretion models. Unlike its DAC-bound counterpart, this peptide is designed to mimic the body’s natural GH pulses by having a short half-life, which enables precise study of hormone dynamics in time-sensitive protocols.
Compound Details
- Molecular Formula: C₁₅₂H₂₄₉N₄₇O₄₂
- Sequence Base: GRF (1-29) with four substitutions to improve stability
- Form: Lyophilized peptide
- Concentration: 5 mg per vial
- Purity: ≥99% (HPLC verified)
- Storage: Store at -20°C. Avoid repeated freeze-thaw cycles. Reconstituted peptide should be used promptly under sterile conditions.
Research Applications
CJC-1295 No DAC is frequently studied in experimental models focused on:
- Pulsatile GH release mapping
- Somatotropic axis modulation
- IGF-1 response kinetics
- Muscle recovery and protein turnover research
- Endocrine feedback loop investigation
Because of its short duration of action, it is particularly useful for evaluating how natural GH pulses impact biological systems under controlled time-series studies.
Mechanism of Interest
Modified GRF (1-29) works by binding to the GHRH receptor, triggering a surge of growth hormone that mimics physiological release patterns. This distinguishes it from longer-acting analogs, making it an optimal peptide for researchers needing fine control over dosing schedules.
Laboratory Use Profile
- Short half-life for acute GH response trials
- Low desensitization in repeat exposure studies
- Allows synchronized GH timing in multi-compound protocols
- Compatible with co-administration studies (e.g., with GHRP/GHS analogs)
Handling Guidelines
- Reconstitute using bacteriostatic water in sterile lab environments
- Refrigerate once mixed (2–8°C)
- Discard any solution not used within research protocol timelines
- For research use only. Not for human or veterinary application.
Compliance Statement
CJC-1295 No DAC (Mod GRF) is not FDA-approved and is offered strictly for laboratory research use only. It is not intended for diagnostic, therapeutic, or any human use.
View Lab Results Here: https://janoshik.com/tests/34607-CJC1295_no_DAC_5MG_L5HV5CD7RNEC
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