Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a peptide-based compound originally developed by researchers at Washington State University. It has been extensively studied in neurobiology labs for its interaction with the hepatocyte growth factor (HGF) and c-Met receptor pathways, which are involved in synaptic plasticity and cognitive processes.
This compound is formulated in oral capsule format for controlled lab experiments where dose uniformity and compound stability are required.
Product Details
- Compound: Dihexa
- Format: 60 capsules per bottle
- Concentration: 5mg per capsule
- Form: Encapsulated peptide (for research use only)
- Storage: Store in a cool, dry place away from direct sunlight. Refrigeration recommended for long-term stability.
Key Research Applications
Dihexa is primarily examined in:
- Neurogenesis and synaptogenesis models
- HGF/c-Met signaling modulation
- Memory and cognition pathways in neurodegenerative models
- Cerebral perfusion studies related to learning tasks
In preclinical settings, Dihexa has demonstrated a potential to enhance synaptic density and restore cognitive function in induced models of cognitive impairment. It is not a cholinesterase inhibitor and does not operate via conventional monoaminergic systems.
Mechanism of Action (In Laboratory Models)
Dihexa binds to HGF and facilitates downstream signaling through the c-Met receptor. This pathway plays a role in:
- Neuronal differentiation and survival
- Axon and dendrite growth
- Synapse formation and remodeling
These properties make Dihexa a unique tool in research centered on plasticity of the central nervous system (CNS) and non-invasive neurorepair pathways.
Notable Research Findings
- Dihexa outperformed traditional neurotrophic agents (e.g., BDNF) in specific spatial memory tests in rodents.
- Studies have also evaluated its potential blood-brain barrier permeability and oral bioavailability in experimental setups.
- It is often examined alongside behavioral models to track dose-dependent memory retention or object-recognition performance.
Handling & Compliance
- For Research Purposes Only.
- Not for human or veterinary use.
- Not approved by the FDA or any regulatory authority for medical use.
Researchers must ensure proper protective handling and follow all local and institutional safety protocols when working with this compound.
There are no reviews yet.