MOTS-c (Mitochondrial-Derived Peptide) – 10 mg Research Vial

For Laboratory Use Only – Not for Human Consumption

Overview

MOTS-c is a 16-amino acid peptide encoded within the 12S rRNA region of mitochondrial DNA. It is under active investigation in metabolic and cellular stress research for its unique role in mitochondrial-nuclear signaling, energy regulation, and homeostatic response models.

This compound is supplied as a high-purity lyophilized powder in sealed sterile vials, intended strictly for controlled laboratory studies.

Product Specifications

Research Focus Areas

MOTS-c is investigated in:

• AMPK Pathway Activation: Studied in models of insulin signaling, mitochondrial biogenesis, and cellular ATP regulation
• Metabolic Regulation: Applied in glucose metabolism, fat oxidation, and stress-response modeling
• Cellular Longevity & Stress Adaptation: Used in experiments related to oxidative stress, aging, and transcriptional response to metabolic strain
• Exercise Physiology Models: Evaluated in skeletal muscle studies for mitochondrial function, metabolic efficiency, and recovery kinetics

Mechanistic Background

In preclinical assays, MOTS-c has demonstrated the ability to:

• Translocate to the nucleus under metabolic stress conditions
• Regulate nuclear gene expression involved in energy metabolism
• Operate independently of the nuclear genome via mitochondrial-origin pathways

These properties make it a unique tool in mitochondrial stress biology and metabolic signaling studies.

Handling & Storage Guidelines

• Reconstitute using sterile technique in approved lab settings
• Avoid repeated freeze–thaw cycles; aliquot as needed
• Use reconstituted solutions promptly or store refrigerated (2–8 °C) per protocol
• Maintain lyophilized vials sealed at –20 °C

Compliance & Regulatory Notice

• §Research Use Only: Not for human or veterinary use
• Not FDA Approved: No claims made regarding therapeutic efficacy, safety, or diagnostic application
• Minimum Purchase Age: 21 years or older
• Prohibited Uses: Not for inclusion in food, supplements, drugs, or therapeutic formulations
• User Responsibility: Compliance with local, state, and federal regulations is required

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Disclaimer

This information is intended solely for scientific documentation and reference. It is not a substitute for medical advice and is not intended to support or imply any clinical use.