MOTS-c

MOTS-c (Mitochondrial-Derived Peptide) is a 16-amino acid peptide encoded within the 12S rRNA region of mitochondrial DNA. It has drawn interest in metabolic and cellular energy research, particularly for its unique role in mitochondrial regulation and adaptation under stress conditions.

Product Specifications

• Compound: MOTS-c
• Form: Lyophilized powder
• Concentration: 10mg per vial
• Purity: >99% (HPLC verified)
• Storage: Store at -20°C; reconstituted solution should be used under sterile conditions and within research safety protocols

Research Focus Areas

MOTS-c has been studied in cellular models and non-human trials focusing on:

• AMPK Pathway Modulation: MOTS-c is observed to activate AMP-activated protein kinase (AMPK), supporting research into cellular energy balance, insulin sensitivity, and mitochondrial biogenesis.
• Metabolic Regulation: It is used in studies modeling glucose metabolism, fat oxidation, and stress-induced metabolic adjustments.
• Age-Related Signaling Models: Experimental research has shown potential roles for MOTS-c in pathways associated with cellular longevity and resistance to oxidative stress.
• Exercise Physiology: Investigated in performance-related studies due to its observed impact on skeletal muscle adaptation and metabolic efficiency.

Mechanistic Highlights

MOTS-c is believed to bypass the nuclear genome and signal directly via mitochondrial-nuclear communication. Research shows that it can translocate to the nucleus during metabolic stress and regulate genes related to energy homeostasis.

Handling Guidelines

• Reconstitute with bacteriostatic water
• Avoid repeated freeze-thaw cycles
• Use appropriate sterile technique in research settings
• Store lyophilized powder at -20°C in a dry, light-protected environment

Important Notice

This compound is for laboratory research only. It is not intended for human consumption or clinical use. It is not approved by the FDA. Purchase is limited to qualified individuals over the age of 21 for licensed research purposes only.

Lab Test Result Available.