SLU-PP-332 – Research-Grade REV-ERBα Agonist (Oral Capsule)
Product Overview
SLU-PP-332 is a synthetic small-molecule compound formulated for laboratory investigation of nuclear receptor signaling, particularly as a selective REV-ERBα agonist. It is supplied in a 100 mcg per capsule format (60-count bottle) to support standardized experimental conditions across metabolic, circadian, and transcriptional pathway research.
Product Specifications
| Attribute | Description |
|---|---|
| Compound | SLU-PP-332 (Synthetic REV-ERBα Agonist) |
| Form | Oral solid capsule |
| Per Capsule Content | 100 mcg |
| Quantity per Bottle | 60 capsules |
| Purity | ≥98% (HPLC-verified) |
| Packaging | Sealed HDPE bottle with tamper-evident seal |
| Storage | Cool, dry environment; avoid light exposure |
| Shelf Life | Stable for 12 months after opening |
| Intended Use | Laboratory and in vitro research only |
Research Applications
SLU-PP-332 has been evaluated in experimental systems investigating:
1. Metabolic Regulation Models
- Gene expression studies related to lipid and glucose metabolism
- Obesity-related transcription factor targeting
- Non-clinical assays of insulin signaling and nutrient partitioning
- Adipocyte activity and fatty acid oxidation tracking
2. Mitochondrial & Energy Studies
- Exploration of CPT1B, UCP1, and PGC-1α transcription
- Mitochondrial respiration, oxidative phosphorylation (OXPHOS) efficiency
- Thermogenic and hepatic energy balance in vitro studies
3. Circadian Rhythm & Transcriptional Assays
- REV-ERBα pathway activation profiling
- In vitro circadian gene clock expression assays
- Molecular chronopharmacology research (e.g., simulated jet lag, light cycle shifts)
All applications are strictly investigational and conducted under controlled, non-human protocols.
Mechanistic Notes (Research Context Only)
SLU-PP-332 acts by modulating transcription via REV-ERBα, a nuclear receptor involved in the repression of pro-inflammatory and lipogenic genes, while supporting pathways related to energy expenditure and mitochondrial efficiency.
No effects have been evaluated in humans. All data is preclinical and for academic or industrial lab study only.
Usage & Handling Guidelines
- Use in approved laboratory environments under sterile handling conditions
- Store below 25°C in a dry, light-protected cabinet
- Maintain strict inventory and usage logs per institutional guidelines
- Do not ingest or administer to humans or animals
Compliance Statement
- Not FDA Approved: This product is not reviewed for safety, efficacy, or any medical purpose.
- Not for Use in Food, Supplements, or Drugs.
- All purchasers must be at least 21 years of age and authorized to work with laboratory-grade research compounds.
For Laboratory Research Use Only – Not for Human or Veterinary Application.
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