Dihexa – Research-Grade Encapsulated Peptide

For Laboratory Use Only – Not for Human or Veterinary Application

Product Overview

Dihexa is a synthetic peptide-based compound originally developed at Washington State University for investigating neurotrophic mechanisms in controlled experimental systems. Extensively studied in preclinical neurobiology models, Dihexa has been examined for its ability to modulate hepatocyte growth factor (HGF) and c-Met receptor signaling pathways associated with synaptic formation and cognitive processes.

This formulation is provided in encapsulated form to support laboratory research requiring precise dosing and enhanced compound stability.

This product is not approved for diagnostic, therapeutic, or veterinary use.

Product Details

Key Research Applications

Dihexa has been investigated in preclinical laboratory settings focusing on:

• Neurogenesis and Synaptogenesis Models
  • Assessment of synaptic density and plasticity in cognitive impairment models
• HGF/c-Met Signaling Studies
  • Analysis of receptor-mediated neuronal survival and differentiation
• Memory and Cognition Research
  • Preclinical evaluation in spatial learning and object recognition tasks
• Cerebral Perfusion and Neurovascular Studies
  • Investigation of non-cholinergic pathways related to cognitive function

All research applications are limited to non-clinical, preclinical models and do not suggest clinical efficacy or safety.

Mechanism of Action (In Laboratory Models)

In experimental settings, Dihexa binds to hepatocyte growth factor (HGF), facilitating c-Met receptor activation. Observed preclinical actions include:

• Promotion of neuronal differentiation and survival
• Support for axonal and dendritic outgrowth
• Facilitation of synaptic remodeling and neuroplasticity

These findings support its utility as a research tool in studies exploring non-invasive neurorepair strategies and central nervous system plasticity.

Notable Research Findings (Preclinical Contexts Only)

• In rodent models, Dihexa demonstrated enhanced outcomes in select spatial memory tasks compared to conventional neurotrophic factors like BDNF.
• Preclinical studies examined blood-brain barrier permeability and oral bioavailability.
• Behavioral assays explored dose-dependent effects on memory retention and learning.

All findings are strictly experimental and should not be interpreted as evidence of safety or efficacy in humans or animals.

Handling & Compliance

• Use only in controlled laboratory environments by trained research personnel
• Handle with appropriate personal protective equipment (PPE)
• Dispose of residual materials in accordance with institutional and regulatory guidelines

Regulatory and Safety Notice

• Research Use Only: For qualified laboratory personnel exclusively
• Not FDA Approved: No medical, diagnostic, or therapeutic claims are made
• Not for Human or Veterinary Consumption: Do not ingest, inject, or administer to humans or animals
• Compliance Responsibility: Researchers must adhere to institutional, local, and federal regulations governing research compounds

Quality Assurance

HVY Research manufactures Dihexa capsules under controlled conditions with rigorous batch testing for purity, identity, and consistency. Researchers must follow established laboratory safety standards, including the use of PPE.

View Lab Result

Disclaimer

This product is intended solely for scientific research purposes. It is not approved for therapeutic, diagnostic, or clinical use and is not for human or animal consumption. All information is provided for scientific reference only.