LL-37 – Synthetic Human Cathelicidin Analog

For Laboratory Research Use Only – Not for Human or Veterinary Application

Product Overview

LL-37 is a synthetic peptide modeled after the human cathelicidin antimicrobial peptide. In laboratory settings, it is evaluated for its activity in innate immune signaling, epithelial defense mechanisms, and regenerative wound healing models. This compound is strictly intended for in vitro and preclinical research protocols conducted by qualified professionals.

It is not approved for therapeutic, diagnostic, or dietary use and is supplied in sterile lyophilized form.

Specifications

Research Applications

LL-37 is utilized in controlled laboratory models focused on:

• Barrier Defense Research – Examining epithelial stabilization in mucosal, dermal, and intestinal systems under inflammatory or microbial stress
• Innate Immunity Studies – Modeling cytokine response, chemotaxis, and host-pathogen interface
• Wound Healing and Epithelial Recovery – Tracking cell migration and tissue regeneration in controlled wound closure assays
• Antimicrobial Peptide Function – Evaluating synthetic analog performance in bacterial membrane interaction assays and immune receptor profiling

All studies remain strictly investigational.

Mechanistic Relevance

• Conserved Peptide Structure – Analogous to naturally secreted LL-37 in epithelial and myeloid cells
• Dual Functional Role – Explores both regenerative and antimicrobial research pathways
• Versatile Lab Use – Applicable in epithelial, pulmonary, gastrointestinal, and ocular models

Handling & Usage Guidelines

• Reconstitute gently using sterile bacteriostatic water
• Do not vortex or over-agitate; mix by slow inversion
• Aliquot after initial reconstitution and freeze unused portions promptly
• Always wear PPE and follow institutional lab safety procedures

Compliance & Disclaimer

• Research Use Only: Not for ingestion, injection, or application to humans or animals
• Not FDA Approved: No safety, efficacy, or therapeutic claims are made
• Purchaser Must Be 21+ and solely responsible for compliant handling
• Prohibited Uses: This product is not sold as a pharmaceutical, supplement, or diagnostic product
• Legal Obligation: User must ensure adherence to local, state, and federal regulations