SS-31 (Elamipretide) – Mitochondrial-Targeted Tetrapeptide
Overview
SS-31, also known as Elamipretide, is a synthetic tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH₂) widely studied in non-clinical research models investigating mitochondrial membrane dynamics, cardiolipin interactions, and oxidative stress response. Designed for laboratory use only, this compound is offered in lyophilized form to support stability and reproducibility in peptide-related assays.
Product Specifications
Attribute | Description |
---|---|
Peptide Name | SS-31 (Elamipretide) |
Molecular Formula | C₄₉H₈₇N₁₃O₇ |
Molecular Weight | ~1023.3 g/mol |
Form | Lyophilized powder |
Purity | ≥98% (HPLC-verified) |
Available Sizes | 10 mg and 50 mg sterile vials |
Solubility | Soluble in sterile bacteriostatic water |
Storage Conditions | Store at –20 °C; protect from light/moisture |
Shelf Life | 24 months (unopened); 30 days (after reconstitution) |
Research Applications
SS-31 has been evaluated in the following investigational contexts:
Mitochondrial Function Studies
- Binding to cardiolipin within the inner mitochondrial membrane
- Assays investigating membrane potential and cristae structural integrity
- In vitro ATP generation and energetic efficiency models
Oxidative Stress Research
- Preclinical models of reactive oxygen species (ROS) regulation
- Studies of mitochondrial preservation during redox imbalance
- Non-clinical oxidative metabolism evaluation
Cellular Aging Pathways
- Models assessing mitochondrial performance in aged tissue systems
- Exploratory research in senescence, skeletal muscle decline, and neuronal cell signaling
Organ Preservation & Ischemia-Reperfusion Models
- Lab studies using cardiac, hepatic, and renal ischemia/reperfusion assays
- Evaluated for cell membrane integrity during controlled oxygen deprivation and recovery
All uses are strictly non-clinical and conducted under qualified laboratory protocols.
Handling & Preparation Guidelines
- Reconstitute with sterile bacteriostatic water only
- Use aseptic technique during all handling steps
- Store reconstituted solution between 2–8°C and use within 30 days
- Avoid multiple freeze-thaw cycles to preserve peptide stability
Regulatory & Compliance Statement
- This product is not a drug, supplement, or treatment
- Not intended for ingestion, injection, or topical application
- All usage must comply with local, state, and federal regulations for research compounds
For Research Use Only – Not for Human or Veterinary Administration.
This compound is not approved for diagnostic, therapeutic, dietary, or cosmetic use in humans or animals.
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